TY - JOUR AU - Creedon, Helen AU - Balderstone, Lucy A. AU - Muir, Morwenna AU - Balla, Jozef AU - Gómez Cuadrado, Laura AU - Tracey, Natasha AU - Loane, Joseph AU - Kilnowska, Teresa AU - Muller, William J. AU - Brunton, Valerie G. PY - 2016 SN - 1754-8403 UR - http://hdl.handle.net/10259/9791 AB - Resistance to human epidermal growth factor receptor 2 (HER2)-targeted therapies presents a major clinical problem. Although preclinical studies have identified a number of possible mechanisms, clinical validation has been difficult. This is most... LA - eng PB - The Company of Biologists KW - HER2 KW - Breast cancer KW - Resistance KW - Epithelial-to-mesenchymal transition KW - Salud KW - Health KW - Oncología KW - Oncology KW - Medicina KW - Medicine TI - Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer DO - 10.1242/dmm.023143 T2 - Disease Models & Mechanisms VL - 9 M2 - 131 ER -