Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10259.4/2523
Título
Role of oleic acid in immune system; mechanism of action; a review
Otro título
Papel del ácido oleico en el sistema inmune: mecanismos de acción: revisión científica
Publicado en
Nutrición Hospitalaria, 2012, v.27, n.4 (julio-agosto), p. 978-990
Editorial
Grupo Aula Médica
Fecha de publicación
2012
ISSN
0212-1611
DOI
10.3305/nh.2012.27.4.5783
Abstract
Introduction:Although n-3 polyunsaturated fatty acids have been widely described as antiinflammatory fats, little is known about the role of oleic acid in immune system.
Aim: The aim of the present review is to join all the reports available in order to analyze where exactly the knowledge concerning this topic is and what the causes of the controversial data could be.
Methods: We searched electronic databases and bibliographies of selected articles were inspected for further reference.
Results:Diets rich in oleic acid have beneficial effects in inflammatory-related diseases. In addition, a wide range of studies evaluate the effect of oleic acid in different cellular functions thus reporting a potential mechanism
for the biological effect of such a fat. However, some controversial data can be found in literature, maybe related to the kind of study or even the dose of the reagent added.
Conclusion:In conclusion, oleic acid could be reported as an anti-inflammatory fatty acid playing a role in the activation of different pathways of immune competent cells.
Palabras clave
Ácido oleico
Sistema inmune
Señalización celular
Oleic acid
Immune system
Intracellular signaling
Materia
Biología molecular
Molecular biology
Versión del editor
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