Ischemic hypoxia, a common condition that can cause neuronal damage, triggers multiple cellular pathways, including hypoxia-inducible factors and anti-apoptotic mechanisms. Using food industry by-products with antioxidant and anti-inflammatory properties, such as melanoidins, as functional ingredients allows their revalorization and may enhance neuronal survival. The scientific impact of this study also considered the bioaccessibility of these compounds to exert a beneficial effect.
