Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10259/3799
Título
Solvent- and ligand-induced switch of selectivity in gold(I)-catalyzed tandem reactions of 3-propargylindoles
Autor
Serie/N.º
Gold catalysis for organic synthesis
Publicado en
Beilstein Journal of Organic Chemistry. 2011, v. 7, p. 786–793
Editorial
Beilstein-Institut
Fecha de publicación
2011-06
ISSN
1860-5397
DOI
10.3762/bjoc.7.89
Abstract
The selectivity of our previously described gold-catalyzed tandem reaction, 1,2-indole migration followed by aura-iso-Nazarov cyclization, of 3-propargylindoles bearing (hetero)aromatic substituents at both the propargylic and terminal positions, was reversed by the proper choice of the catalyst and the reaction conditions. Thus, 3-(inden-2-yl)indoles, derived from an aura-Nazarov cyclization (instead of an aura-iso-Nazarov cyclization), were obtained in moderate to good yields from a variety of 3-propargylindoles
Palabras clave
catalysis
gold
indoles
Nazarov cyclizations
selectivity
Materia
Química orgánica
Chemistry, Organic
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