Determinación analítica de antibióticos

Abstract

Annual global aquaculture production has more than tripled within the past 20 years, and by 2015, aquaculture is predicted to account for 40 % of total global seafood production by weight. As production surges, aquaculture facilities increasingly rely on the heavy input of formulated feeds, antibiotics, antifungals and agrochemicals, which could have potential impacts on public health [1]. In particular, the risk of bacterial infections among aquacultured fish is high as a result of the non-hygienic and stressful conditions present in aquaculture facilities, including high fish densities, high farm densities in coastal waters and lack of appropriate barriers between farms. Therefore, heavy amounts of antibiotics, which kill bacteria or inhibit their growth, are administered in fish feed for prophylactic (disease prevention) and therapeutic (disease treatment) purposes in aquaculture facilities worldwide [1]. However, the antibiotics can contribute to resistance among bacteria [2]. Thus, it is necessary to develop analytical methods that can detect antibiotics with the greatest sensitivity and selectivity possible. In this way, electroanalytical sensors provide an achievable opportunity to perform biomedical, environmental and industrial analyses away from a centralized laboratory. In particular, screen-printed electrodes (SPEs) can combine ease of use and portability with simple, inexpensive fabrication techniques. Although early SPEs sensors focused on the determination of glucose in blood samples, since then applications have broadened to include the determination of other biomolecules, pesticides, metals, anions and potential pollutants [2-4]. Thus, this work has been guided to the development of analytical procedures based on the use of SPEs for the detection of the above-mentioned antibiotics in water samples