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| dc.contributor.author | Álvarez Manuel, Estela | |
| dc.contributor.author | Nieto Faza, Olalla . | |
| dc.contributor.author | Silva López, Carlos | |
| dc.contributor.author | Fernández Rodríguez, Manuel A. | |
| dc.contributor.author | Sanz Díez, Roberto | |
| dc.date.accessioned | 2016-11-22T09:15:54Z | |
| dc.date.available | 2016-11-22T09:15:54Z | |
| dc.date.issued | 2015-09 | |
| dc.identifier.issn | 0947-6539 | |
| dc.identifier.uri | http://hdl.handle.net/10259/4278 | |
| dc.description.abstract | A cascade reaction of indoles with propargylic diols involving an unprecedented metal-free 1,2-indole migration onto an alkyne is here described. DFT calculations support a mechanism consisting in a concerted nucleophilic attack of the indole nucleus with loss of water followed by the 1,2-migration and subsequent Nazarov cyclization. This Brønsted acid-catalyzed protocol affords indole-functionalized benzofulvene derivatives in high yields. | en |
| dc.description.sponsorship | Junta de Castilla y León(BU237U13) and Ministerio de Economía y Competitividad (MINECO) and FEDER (CTQ2013-48937-C2-1P and 2-P) | en |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | eng | es |
| dc.publisher | Wiley-VCH Verlag | en |
| dc.relation.ispartof | Chemistry-a european journal. 2015, V. 21, n. 37, p. 12889–12893 | en |
| dc.subject | benzofulvenes | en |
| dc.subject | Brønsted acid | en |
| dc.subject | catalysis | en |
| dc.subject | indolemigration | en |
| dc.subject | Nazarov cyclization | en |
| dc.subject.other | Chemistry, Organic | en |
| dc.subject.other | Química orgánica | es |
| dc.title | Brønsted Acid-Catalyzed Cascade Reactions Involving 1,2-Indole Migration | en |
| dc.type | info:eu-repo/semantics/article | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.relation.publisherversion | http://dx.doi.org/10.1002/chem.201502174 | |
| dc.type.hasVersion | info:eu-repo/semantics/acceptedVersion | en |
