Ver item 

Mostrar registro simples

dc.contributor.authorÁlvarez Manuel, Estela 
dc.contributor.authorNieto Faza, Olalla .
dc.contributor.authorSilva López, Carlos
dc.contributor.authorFernández Rodríguez, Manuel A. 
dc.contributor.authorSanz Díez, Roberto 
dc.date.accessioned2016-11-22T09:15:54Z
dc.date.available2016-11-22T09:15:54Z
dc.date.issued2015-09
dc.identifier.issn0947-6539
dc.identifier.urihttp://hdl.handle.net/10259/4278
dc.description.abstractA cascade reaction of indoles with propargylic diols involving an unprecedented metal-free 1,2-indole migration onto an alkyne is here described. DFT calculations support a mechanism consisting in a concerted nucleophilic attack of the indole nucleus with loss of water followed by the 1,2-migration and subsequent Nazarov cyclization. This Brønsted acid-catalyzed protocol affords indole-functionalized benzofulvene derivatives in high yields.en
dc.description.sponsorshipJunta de Castilla y León(BU237U13) and Ministerio de Economía y Competitividad (MINECO) and FEDER (CTQ2013-48937-C2-1P and 2-P)en
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherWiley-VCH Verlagen
dc.relation.ispartofChemistry-a european journal. 2015, V. 21, n. 37, p. 12889–12893en
dc.subjectbenzofulvenesen
dc.subjectBrønsted aciden
dc.subjectcatalysisen
dc.subjectindolemigrationen
dc.subjectNazarov cyclizationen
dc.subject.otherChemistry, Organicen
dc.subject.otherQuímica orgánicaes
dc.titleBrønsted Acid-Catalyzed Cascade Reactions Involving 1,2-Indole Migrationen
dc.typeinfo:eu-repo/semantics/article
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.relation.publisherversionhttp://dx.doi.org/10.1002/chem.201502174
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersionen


Arquivos deste item

Thumbnail
Nome:
Álvarez-CEJ_2015.pdf
Tamanho:
730.2Kb
Formato:
Adobe PDF
Visualizar/Abrir

Este item aparece na(s) seguinte(s) coleção(s)

Mostrar registro simples