A new and selective voltammetric method for chloride determination is proposed, based on platinum and chloride interactions. A screen-printed platinum electrode (SPPtE) functions as a sensing platform, which promotes the formation of chloro-adsorbed species on the electrode surface, acting as an effective means of anion-determination in several matrices. The pretreatment of the SPPtE and careful control of the cathodic stripping voltammetric parameters yielded a well-defined electrochemical signal. This cathodic peak was due to the adsorption of chlorine, which had previously been oxidized from chloride anions in the initial anodic deposition step. It offers a simple, low-cost, fast, reproducible (RSD < 6%) and precise method for selective chloride determination, with limit of detection of 0.76 mM, and a sensitivity of − 24.147 µA mM −1 for a broad determination range of up to 150 mM. Chloride determination was correctly performed with single drops of environmental, pharmaceutical and food samples. In addition, the sensor was successfully adapted as a flexible screen-printed platinum electrode sensor using Gore-Tex® as support for printing.
