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dc.contributor.authorRumbo Lorenzo, Carlos 
dc.contributor.authorCancho Espina, Cristina
dc.contributor.authorPopov, Vladimir V.
dc.contributor.authorSkokov, Konstantin
dc.contributor.authorTamayo Ramos, Juan Antonio 
dc.date.accessioned2020-10-19T08:22:30Z
dc.date.available2020-10-19T08:22:30Z
dc.date.issued2021-01
dc.identifier.issn0045-6535
dc.identifier.urihttp://hdl.handle.net/10259/5518
dc.description.abstractDue to economic, environmental and geopolitical issues, the development of permanent magnets with a composition free of rare earth elements and with acceptable magnetic properties has been considered a priority by the international community, being MnAl based alloys amongst the most promising candidates. The aim of this work was to evaluate the toxicity of powders of two forms of newly developed MnAl(C) permanent magnets through exposure experiments applying three model organisms, using as a benchmark powders of a commercial rare-earth-containing magnet (Nd2Fe14B). For this purpose, the direct exposure to the different particles suspensions as well as to magnets leachates was evaluated. Both viability and oxidative stress assays were applied in an adenocarcinomic human alveolar basal epithelial cell line (A549) and in the yeast Saccharomyces cerevisiae, together with the bioluminescent inhibition assay in the Gram negative bacterium Vibrio fischeri. The obtained results indicate that MnAl(C) permanent magnets, in general terms, presented similar toxicity than the Nd magnet for the selected biological models under the studied conditions. Overall, the presented data provide, for the first time, an in vitro toxicity analysis of MnAl based magnets.en
dc.description.sponsorshipEuropean Union’s Horizon 2020 NOVAMAG project (NMBP 23-2015, grant agreement N 686056) and from the Junta de Castilla y Leon and the European Social Fund-Youth European Initiative grant UBU-15-A.es
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherElsevieres
dc.relation.ispartofChemosphere.2021, V. 263, 128343es
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectMagnetic alloysen
dc.subjectToxicity assaysen
dc.subjectCell linesen
dc.subjectYeasten
dc.subjectBacteriaen
dc.subject.otherQuímica orgánicaes
dc.subject.otherChemistry, Organicen
dc.titleToxicological evaluation of MnAl based permanent magnets using different in vitro modelsen
dc.typeinfo:eu-repo/semantics/article
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.relation.publisherversionhttps://doi.org/10.1016/j.chemosphere.2020.128343
dc.identifier.doi10.1016/j.chemosphere.2020.128343
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/686056
dc.relation.projectIDinfo:eu-repo/grantAgreement/JCyL/UBU-15-A
dc.journal.titleChemospherees
dc.volume.number263es
dc.page.initial128343es
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion


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