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dc.contributor.authorAlves Elois, Mariana
dc.contributor.authorSilva, Raphael da
dc.contributor.authorPilati, Giulia
dc.contributor.authorRodríguez Lázaro, David 
dc.contributor.authorFongaro, Gislaine
dc.date.accessioned2023-03-20T08:25:19Z
dc.date.available2023-03-20T08:25:19Z
dc.date.issued2023-01
dc.identifier.urihttp://hdl.handle.net/10259/7557
dc.description.abstractBacteriophages are ubiquitous organisms that can be specific to one or multiple strains of hosts, in addition to being the most abundant entities on the planet. It is estimated that they exceed ten times the total number of bacteria. They are classified as temperate, which means that phages can integrate their genome into the host genome, originating a prophage that replicates with the host cell and may confer immunity against infection by the same type of phage; and lytics, those with greater biotechnological interest and are viruses that lyse the host cell at the end of its reproductive cycle. When lysogenic, they are capable of disseminating bacterial antibiotic resistance genes through horizontal gene transfer. When professionally lytic—that is, obligately lytic and not recently descended from a temperate ancestor—they become allies in bacterial control in ecological imbalance scenarios; these viruses have a biofilm-reducing capacity. Phage therapy has also been advocated by the scientific community, given the uniqueness of issues related to the control of microorganisms and biofilm production when compared to other commonly used techniques. The advantages of using bacteriophages appear as a viable and promising alternative. This review will provide updates on the landscape of phage applications for the biocontrol of pathogens in industrial settings and healthcare.en
dc.description.sponsorshipThis study was funded by CNPQ and the Federal University of Santa Catarina, SIGPEX UFSC–201917940.en
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherMDPIen
dc.relation.ispartofViruses. 2023, V. 15, n. 2, 349en
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectBacteriophagesen
dc.subjectApplicationsen
dc.subjectBiotechnologicalen
dc.subject.otherMicrobiologíaes
dc.subject.otherMicrobiologyen
dc.titleBacteriophages as Biotechnological Toolsen
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://doi.org/10.3390/v15020349es
dc.identifier.doi10.3390/v15020349
dc.relation.projectIDinfo:eu-repo/grantAgreement/UFSC//201917940/BR/es
dc.identifier.essn1999-4915
dc.journal.titleVirusesen
dc.volume.number15es
dc.issue.number2es
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones


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