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dc.contributor.authorCarpio, Ana
dc.contributor.authorCebrián de Barrio, Elena 
dc.contributor.authorVidal, Perfecto
dc.date.accessioned2024-01-09T11:31:40Z
dc.date.available2024-01-09T11:31:40Z
dc.date.issued2019
dc.identifier.issn0020-7462
dc.identifier.urihttp://hdl.handle.net/10259/8262
dc.description.abstractBiofilms are bacterial aggregates encased in a self-produced polymeric matrix which attach to moist surfaces and are extremely resistant to chemicals and antibiotics. Recent experiments show that their structure is defined by the interplay of elastic deformations and liquid transport within the biofilm, in response to the cellular activity and the interaction with the surrounding environment. We propose a poroelastic model for elastic deformation and liquid transport in three dimensional biofilms spreading on agar surfaces. The motion of the boundaries can be described by the combined use of Von Kármán type approximations for the agar/biofilm interface and thin film approximations for the biofilm/air interface. Bacterial activity informs the macroscopic continuous model through source terms and residual stresses, either phenomenological or derived from microscopic models. We present a procedure to estimate the structure of such residual stresses, based on a simple cellular automata description of bacterial activity. Inspired by image processing, we show that a filtering strategy effectively smooths out the rough tensors provided by the stochastic cellular automata rules, allowing us to insert them in the macroscopic model without numerical instability.en
dc.description.sponsorshipThis research has been supported by MINECO grants No. MTM2014-56948-C2-1-P, No. MTM2017-84446-C2-1-R and No. PRX18-00112.en
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherElsevieres
dc.relation.ispartofInternational Journal of Non-Linear Mechanics. 2019, V. 109, p. 1-8es
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectBiofilmen
dc.subjectPoroelasticen
dc.subjectVon Kármánen
dc.subjectThin filmen
dc.subjectCellular automataen
dc.subjectTotal variation based filteren
dc.subject.otherMicrobiologíaes
dc.subject.otherMicrobiologyen
dc.subject.otherMatemáticases
dc.subject.otherMathematicsen
dc.titleBiofilms as poroelastic materialsen
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://doi.org/10.1016/j.ijnonlinmec.2018.10.012es
dc.identifier.doi10.1016/j.ijnonlinmec.2018.10.012
dc.journal.titleInternational Journal of Non-Linear Mechanicsen
dc.volume.number109es
dc.page.initial1es
dc.page.final8es
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersiones


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