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dc.contributor.authorSáiz Vázquez, Olalla 
dc.contributor.authorPuente Martínez, Alicia
dc.contributor.authorUbillos Landa, Silvia 
dc.contributor.authorPacheco Bonrostro, Joaquín 
dc.contributor.authorSantabárbara, Javier
dc.date.accessioned2024-02-19T11:36:03Z
dc.date.available2024-02-19T11:36:03Z
dc.date.issued2020-06
dc.identifier.urihttp://hdl.handle.net/10259/8700
dc.description.abstractAlzheimer’s disease (AD) is the most common subtype of dementia. In the last ten years, the relationship between cholesterol and AD has been investigated. Evidence suggests that cholesterol is associated with AD and represents promising targets for intervention. However, the causality of these associations is unclear. Therefore, we sought to conduct a meta-meta-analysis to determine the effect of cholesterol on the development AD. Then, we assessed the effect of serum levels of low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and triglycerides (TG), on AD risk.en
dc.description.sponsorshipThis research was funded by a research grant from the Basque Country, Spain (awarded to A.P.), by the Junta of Castilla y León (Spain) to the Social Inclusion and Quality of Life (SIQoL) (No.665501), by FEDER funds and the Spanish Ministry of Economy and Competitiveness (Projects ECO2013-47129-C4-3-R and ECO2016-76567-C4-2-R), by the Regional Government of Castilla y León and FEDER funds (Projects BU329U14, BU071G19 and BU062U16), and by the Fondo de Investigación Sanitaria, Instituto de Salud Carlos III, Spanish Ministry of Economy and Competitiveness, Madrid, Spain (grants 94/1562, 97/1321E, 98/0103, 01/0255, 03/0815, 06/0617, G03/128, 19/01874).en
dc.language.isoenges
dc.publisherMDPIen
dc.relation.ispartofBrain Sciences. 2020, V. 10, n. 6, 386en
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAlzheimer's diseaseen
dc.subjectEtiologyen
dc.subjectCholesterolen
dc.subjectRisk factorsen
dc.subjectMeta-analysisen
dc.subject.otherMedicinaes
dc.subject.otherMedicineen
dc.subject.otherSaludes
dc.subject.otherHealthen
dc.subject.otherPsicologíaes
dc.subject.otherPsychologyen
dc.titleCholesterol and Alzheimer’s Disease Risk: A Meta-Meta-Analysisen
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://doi.org/10.3390/brainsci10060386es
dc.identifier.doi10.3390/brainsci10060386
dc.identifier.essn2076-3425
dc.journal.titleBrain Sciencesen
dc.volume.number10es
dc.issue.number6es
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones


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