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dc.contributor.authorHernández Gallego, Jesús
dc.contributor.authorLlamas Velasco, Sara
dc.contributor.authorBermejo Pareja, Félix
dc.contributor.authorVega, Saturio
dc.contributor.authorTapias Merino, Ester
dc.contributor.authorRodríguez Sánchez, Emiliano
dc.contributor.authorBoycheva, Elina
dc.contributor.authorSerrano, José Ignacio
dc.contributor.authorGil García, Juan Francisco
dc.contributor.authorTrincado, Rocío
dc.contributor.authorVizcaino Sánchez-Rodrigo, José María
dc.contributor.authorCacho, Jesús
dc.contributor.authorContador, Israel
dc.contributor.authorGarcía Ptacek, Sara
dc.contributor.authorSierra Hidalgo, Fernando
dc.contributor.authorCubo Delgado, Esther 
dc.contributor.authorCarro, Eva
dc.contributor.authorVillarejo Galende, Alberto
dc.contributor.authorGarcía García-Patino, Rosalía
dc.contributor.authorBenito-León, Julián
dc.date.accessioned2024-03-08T12:15:16Z
dc.date.available2024-03-08T12:15:16Z
dc.date.issued2019-01
dc.identifier.urihttp://hdl.handle.net/10259/8785
dc.description.abstractBackground: The Neurological Disorders in Central Spain, second survey (NEDICES-2) is a population-based, closed-cohort study that will include over 8000 subjects aged ≥55 years. It will also include a biobank. Objective: The objective of this study was to evaluate all major aspects of the NEDICES-2 (methods, database, screening instruments, and questionnaires, as well as interexpert rating of the neurological diagnoses) in each one of the planned areas (all of them in central Spain) and to test the possibility of obtaining biological samples from each participant. Methods: A selection of patients and participants of the planned NEDICES-2 underwent face-to-face interviews including a comprehensive questionnaire on demographics, current medications, medical conditions, and lifestyle habits. Biological samples (blood, saliva, urine, and hair) were also obtained. Furthermore, every participant was examined by a neurologist. Results: In this pilot study, 567 study participants were enrolled (196 from hospitals and 371 from primary care physician lists). Of these 567, 310 completed all study procedures (questionnaires and the neurological evaluation). The study was time-consuming for several primary care physicians. Hence, a few primary care physicians from some areas refused to participate, which led to a reconfiguration of study areas. In addition, the central biobank needed to be supplemented by the biobanks of local Spanish National Health System hospitals. Conclusions: Population-based epidemiological surveys, such as the NEDICES-2, require a pilot study to evaluate the feasibility of all aspects of a future field study (population selection, methods and instruments to be used, neurological diagnosis agreement, and data collection).en
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherJMIR Publicationsen
dc.relation.ispartofJMIR Research Protocols. 2019, V. 8, n. 1, e10941en
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectDementiaen
dc.subjectEssential tremoren
dc.subjectHeadacheen
dc.subjectLongitudinal studyen
dc.subjectMild cognitive impairmenten
dc.subjectNEDICESen
dc.subjectObservational studyen
dc.subjectParkinson’s diseaseen
dc.subjectPilot studyen
dc.subjectPopulation-based studyen
dc.subjectStrokeen
dc.subject.otherSistema nervioso-Enfermedadeses
dc.subject.otherNervous system-Diseasesen
dc.subject.otherNeurologíaes
dc.subject.otherNeurologyen
dc.subject.otherMedicinaes
dc.subject.otherMedicineen
dc.titleNeurological Disorders in Central Spain, Second Survey: Feasibility Pilot Observational Studyen
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://www.researchprotocols.org/2019/1/e10941/es
dc.identifier.doidoi:10.2196/10941
dc.identifier.essn1929-0748
dc.journal.titleJMIR Research Protocolsen
dc.volume.number8es
dc.issue.number1es
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones


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