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dc.contributor.authorSantos García, Diego
dc.contributor.authorSuárez Castro, Ester
dc.contributor.authorDeus-Fonticoba, Teresa de
dc.contributor.authorFeal Panceiras, M. J.
dc.contributor.authorMuñoz Enríquez, J. G.
dc.contributor.authorPaz González, José Manuel
dc.contributor.authorCores Bartolomé, Carlos
dc.contributor.authorPlanellás, Lluis L.
dc.contributor.authorGarcía Caldentey, Juan
dc.contributor.authorCaballol, Núria
dc.contributor.authorLegarda, Inés
dc.contributor.authorCabo López, Iria
dc.contributor.authorLópez Manzanares, Lydia
dc.contributor.authorÁvila Rivera, María A.
dc.contributor.authorCatalán, María José
dc.contributor.authorNogueira, Víctor
dc.contributor.authorBorrue, Carmen
dc.contributor.authorÁlvarez Saúco, María
dc.contributor.authorVela Desojo, Lydia
dc.contributor.authorCubo Delgado, Esther 
dc.contributor.authorMartínez Castrillo, Juan Carlos
dc.contributor.authorSánchez Alonso, Pilar
dc.contributor.authorAlonso Losada, María Gema
dc.contributor.authorLópez Ariztegui, Nuria
dc.contributor.authorGastón, Itziar
dc.contributor.authorKulisevsky Bojarsky, Jaume
dc.contributor.authorPagonabarraga, Javier
dc.contributor.authorSeijo, Manuel
dc.contributor.authorRuíz Martínez, Javier
dc.contributor.authorValero, Caridad
dc.contributor.authorKurtis, Mónica M.
dc.contributor.authorGonzález Ardura, Jessica
dc.contributor.authorPrieto, Cristina
dc.contributor.authorMir, Pablo
dc.contributor.authorMartínez Martín, Pablo
dc.contributor.authorCOPPADIS Study Group
dc.date.accessioned2024-03-12T08:29:39Z
dc.date.available2024-03-12T08:29:39Z
dc.date.issued2020-10
dc.identifier.issn0891-9887
dc.identifier.urihttp://hdl.handle.net/10259/8803
dc.description.abstractIntroduction: The aim of the present study was to examine the frequency of self-reported sleep problems and their associated factors in a large cohort of PD patients. Methods: PD patients and controls, recruited from 35 centers of Spain from the COPPADIS cohort were included in this cross-sectional study. Sleep problems were assessed by the Spanish version of the Parkinson’s disease Sleep Scale version 1 (PDSS-1). An overall score below 82 or a score below 5 on at least 1 item was defined as sleep problems. Results: The frequency of sleep problems was nearly double in PD patients compared to controls: 65.8% (448/681) vs 33.5% (65/206) (p < 0.0001). Mean total PDSS score was lower in PD patients than controls: 114.9 ± 28.8 vs 132.8 ± 16.3 (p < 0.0001). Quality of life (QoL) was worse in PD patients with sleep problems compared to those without: PDQ-39SI, 19.3 ± 14 vs 13 ± 11.6 (p < 0.0001); EUROHIS-QoL8, 3.7 ± 0.5 vs 3.9 ± 0.5 (p < 0.0001). Non-motor symptoms burden (NMSS; OR = 1.029; 95%CI 1.015–1.043; p < 0.0001) and impulse control behaviors (QUIP-RS; OR = 1.054; 95%CI 1.009–1.101; p = 0.018) were associated with sleep problems after adjustment for age, gender, disease duration, daily equivalent levodopa dose, H&Y, UPDRS-III, UPDRS-IV, PD-CRS, BDI-II, NPI, VAS-Pain, VAFS, FOGQ, and total number of non-antiparkinsonian treatments. Conclusion: Sleep problems were frequent in PD patients and were related to both a worse QoL and a greater non-motor symptoms burden in PD. These findings call for increased awareness of sleep problems in PD patients.en
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherSAGE Publicationsen
dc.relation.ispartofJournal of Geriatric Psychiatry and Neurology. 2021, V. 34, n. 6, p. 642-658en
dc.subjectNon-motor symptomsen
dc.subjectParkinson’s diseaseen
dc.subjectParkinson’s disease sleep scaleen
dc.subjectQuality of lifeen
dc.subjectSleepen
dc.subject.otherSistema nervioso-Enfermedadeses
dc.subject.otherNervous system-Diseasesen
dc.subject.otherMedicinaes
dc.subject.otherMedicineen
dc.subject.otherNeurologíaes
dc.subject.otherNeurologyen
dc.titleSleep Problems Are Related to a Worse Quality of Life and a Greater Non-Motor Symptoms Burden in Parkinson’s Diseaseen
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://doi.org/10.1177/0891988720964250es
dc.identifier.doi10.1177/0891988720964250
dc.identifier.essn1552-5708
dc.journal.titleJournal of Geriatric Psychiatry and Neurologyen
dc.volume.number34es
dc.issue.number6es
dc.page.initial642es
dc.page.final658es
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones


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