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dc.contributor.authorSantos García, Diego
dc.contributor.authorDeus-Fonticoba, Teresa de
dc.contributor.authorCores Bartolomé, Carlos
dc.contributor.authorSuárez Castro, Ester
dc.contributor.authorHernández Vara, Jorge
dc.contributor.authorJesús, Silvia
dc.contributor.authorMir, Pablo
dc.contributor.authorCosgaya, Marina
dc.contributor.authorJosé Martí, María
dc.contributor.authorPastor, Pau
dc.contributor.authorCabo López, Iria
dc.contributor.authorSeijo, Manuel
dc.contributor.authorLegarda, Inés
dc.contributor.authorVives Pastor, Bárbara
dc.contributor.authorCaballol, Núria
dc.contributor.authorRuíz Martínez, Javier
dc.contributor.authorCroitoru, Ioana
dc.contributor.authorCubo Delgado, Esther 
dc.contributor.authorMiranda, Javier
dc.contributor.authorAlonso Losada, María Gema
dc.contributor.authorLabandeira, Carmen
dc.contributor.authorLópez Ariztegui, Nuria
dc.contributor.authorMorales-Casado, Mabel
dc.contributor.authorGonzález Aramburu, Isabel
dc.contributor.authorInfante, Jon
dc.contributor.authorEscalante Arroyo, Sonia
dc.contributor.authorBernardo, Noemí
dc.contributor.authorBlázquez Estrada, Marta
dc.contributor.authorMenéndez González, Manuel
dc.contributor.authorGarcía Caldentey, Juan
dc.contributor.authorBorrue, Carmen
dc.contributor.authorVela Desojo, Lydia
dc.contributor.authorCatalán, María José
dc.contributor.authorGómez Mayordomo, Víctor
dc.contributor.authorKurtis, Mónica M.
dc.contributor.authorPrieto, Cristina
dc.contributor.authorOrdás Bandera, Carlos Manuel
dc.contributor.authorNogueira, Víctor
dc.contributor.authorLópez Manzanares, Lydia
dc.contributor.authorÁvila Rivera, María A.
dc.contributor.authorPuente, Víctor
dc.contributor.authorGarcía Moreno, José Manuel
dc.contributor.authorSolano Vila, Berta
dc.contributor.authorÁlvarez Saúco, María
dc.contributor.authorCarrillo Padilla, Francisco
dc.contributor.authorMartínez Castrillo, Juan Carlos
dc.contributor.authorSánchez Alonso, Pilar
dc.contributor.authorGastón, Itziar
dc.contributor.authorKulisevsky Bojarsky, Jaume
dc.contributor.authorValero, Caridad
dc.contributor.authorFabregues, Oriol de
dc.contributor.authorGonzález Ardura, Jessica
dc.contributor.authorLópez Díaz, Luis M.
dc.contributor.authorMartínez Martín, Pablo
dc.contributor.authorCOPPADIS Study Group
dc.date.accessioned2024-03-18T10:37:48Z
dc.date.available2024-03-18T10:37:48Z
dc.date.issued2023-01
dc.identifier.issn1877-7171
dc.identifier.urihttp://hdl.handle.net/10259/8839
dc.description.abstractBackground: There is a need for identifying risk factors for hospitalization in Parkinson’s disease (PD) and also interventions to reduce acute hospital admission. Objective: To analyze the frequency, causes, and predictors of acute hospitalization (AH) in PD patients from a Spanish cohort. Methods: PD patients recruited from 35 centers of Spain from the COPPADIS-2015 (COhort of Patients with PArkinson’s DIsease in Spain, 2015) cohort from January 2016 to November 2017, were included in the study. In order to identify predictors of AH, Kaplan-Meier estimates of factors considered as potential predictors were obtained and Cox regression performed on time to hospital encounter 1-year after the baseline visit. Results: Thirty-five out of 605 (5.8%) PD patients (62.5±8.9 years old; 59.8% males) presented an AH during the 1-year follow-up after the baseline visit. Traumatic falls represented the most frequent cause of admission, being 23.7% of all acute hospitalizations. To suffer from motor fluctuations (HR [hazard ratio] 2.461; 95% CI, 1.065–5.678; p = 0.035), a very severe non-motor symptoms burden (HR [hazard ratio] 2.828; 95% CI, 1.319–6.063; p = 0.008), falls (HR 3.966; 95% CI 1.757–8.470; p = 0.001), and dysphagia (HR 2.356; 95% CI 1.124–4.941; p = 0.023) was associated with AH after adjustment to age, gender, disease duration, levodopa equivalent daily dose, total number of non-antiparkinsonian drugs, and UPDRS-IIIOFF. Of the previous variables, only falls (HR 2.998; 95% CI 1.080–8.322; p = 0.035) was an independent predictor of AH. Conclusion: Falls is an independent predictor of AH in PD patients.en
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherIOS Pressen
dc.relation.ispartofJournal of Parkinson's Disease. 2023, V. 13, n. 1, p. 105-124en
dc.rightsAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectFallsen
dc.subjectHospitalizationen
dc.subjectNon-motor symptomsen
dc.subjectParkinson’s diseaseen
dc.subjectPredictorsen
dc.subject.otherSistema nervioso-Enfermedadeses
dc.subject.otherNervous system-Diseasesen
dc.subject.otherMedicinaes
dc.subject.otherMedicineen
dc.subject.otherNeurologíaes
dc.subject.otherNeurologyen
dc.titleFalls Predict Acute Hospitalization in Parkinson’s Diseaseen
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://content.iospress.com/articles/journal-of-parkinsons-disease/jpd212539es
dc.identifier.doi10.3233/JPD-212539
dc.identifier.essn1877-718X
dc.journal.titleJournal of Parkinson's Diseaseen
dc.volume.number13es
dc.issue.number1es
dc.page.initial105es
dc.page.final124es
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones


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