RT info:eu-repo/semantics/article
T1 Adequacy of an Altitude Fitness Program (Living and Training) plus Intermittent Exposure to Hypoxia for Improving Hematological Biomarkers and Sports Performance of Elite Athletes: A Single-Blind Randomized Clinical Trial
A1 Fernández-Lázaro, Diego
A1 Mielgo Ayuso, Juan
A1 Santamaría, Gema
A1 Gutiérrez-Abejón, Eduardo
A1 Domínguez-Ortega, Carlos
A1 García-Lázaro, Sandra María
A1 Seco-Calvo, Jesús
K1 Hypoxia
K1 Athletes
K1 Blood biomarkers
K1 Sports performance
K1 Safety profile
K1 Altitude training
K1 Fisiología
K1 Physiology
AB Athletes incorporate altitude training programs into their conventional training to improvetheir performance. The purpose of this study was to determine the effects of an 8-week altitudetraining program that was supplemented with intermittent hypoxic training (IHE) on the bloodbiomarkers, sports performance, and safety profiles of elite athletes. In a single-blind randomizedclinical trial that followed the CONSORT recommendations, 24 male athletes were randomized toan IHE group (HA, n = 12) or an intermittent normoxia group (NA, n = 12). The IHE consistedof 5-min cycles of hypoxia–normoxia with an FIO2 of between 10–13% for 90 min every day for8 weeks. Hematological (red blood cells, hemoglobin, hematocrit, hematocrit, reticulated hemoglobin,reticulocytes, and erythropoietin), immunological (leukocytes, monocytes, and lymphocytes), andrenal (urea, creatinine, glomerular filtrate, and total protein) biomarkers were assessed at the baseline(T1), day 28 (T2), and day 56 (T3). Sports performance was evaluated at T1 and T3 by measuringquadriceps strength and using three-time trials over the distances of 60, 400, and 1000 m on anathletics track. Statistically significant increases (p < 0.05) in erythropoietin, reticulocytes, hemoglobin,and reticulocyte hemoglobin were observed in the HA group at T3 with respect to T1 and the NAgroup. In addition, statistically significant improvements (p < 0.05) were achieved in all performancetests. No variations were observed in the immunological or renal biomarkers. The athletes who wereliving and training at 1065 m and were supplemented with IHE produced significant improvementsin their hematological behavior and sports performance with optimal safety profiles.
PB MDPI
YR 2022
FD 2022-07
LK http://hdl.handle.net/10259/7589
UL http://hdl.handle.net/10259/7589
LA eng
DS Repositorio Institucional de la Universidad de Burgos
RD 01-may-2024