TY - JOUR AU - Ayllón Barasoain, Juan AU - Domingues, Patricia AU - Rajsbaum, Ricardo AU - Miorin, Lisa AU - Schmolke, Mirco AU - Hale, Benjamin G. AU - García Sastre, Adolfo PY - 2014 SN - 0022-538X UR - http://hdl.handle.net/10259/7995 AB - Although an effective interferon antagonist in human and avian cells, the novel H7N9 influenza virus NS1 protein is defective at inhibiting CPSF30. An I106M substitution in H7N9 NS1 can restore CPSF30 binding together with the ability to block host... LA - eng PB - American Society for Microbiology KW - Medicina KW - Medicine KW - Microbiología KW - Microbiology KW - Salud KW - Health KW - Enfermedades infecciosas KW - Communicable diseases TI - A Single Amino Acid Substitution in the Novel H7N9 Influenza A Virus NS1 Protein Increases CPSF30 Binding and Virulence DO - 10.1128/JVI.01567-14 T2 - Journal of Virology VL - 88 M2 - 12146 ER -