TY - JOUR AU - Fernández Díaz, Cristina M. . AU - Merino, Beatriz AU - López Acosta, J.F. AU - Cidad, Pilar AU - Fuente, Miguel A. de la AU - Lobatón, Carmen D. AU - Moreno, Alfredo AU - Leissring, Malcolm A. AU - Perdomo Hernández, Germán M. AU - Cózar Castellano, Irene PY - 2019 SN - 0193-1849 UR - http://hdl.handle.net/10259/5244 AB - Inhibition of insulin-degrading enzyme (IDE) has been proposed as a possible therapeutic target for type 2 diabetes treatment. However, many aspects of IDE's role in glucose homeostasis need to be clarified. In light of this, new preclinical models... LA - eng PB - American Physiological Society KW - Endocrinología KW - Endocrinology TI - Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity DO - 10.1152/ajpendo.00040.2019 T2 - American Journal of Physiology-Endocrinology and Metabolism VL - 317 M2 - E805 ER -