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dc.contributor.advisor | Domínguez Renedo, Olga | |
dc.contributor.author | Sancho Querol, Sara | |
dc.contributor.other | Universidad de Burgos. Departamento de Química | |
dc.date.accessioned | 2014-10-21T10:06:26Z | |
dc.date.available | 2014-10-21T10:06:26Z | |
dc.date.submitted | 2014 | |
dc.identifier.uri | http://hdl.handle.net/10259/3533 | |
dc.description.abstract | This work reports the development of two different sensors using screen-printed carbon electrodes (SPCEs) for the determination of imipramine (IMP) by differential pulse voltammetry. On one hand, a bare SPCE has been successfully applied to the determination of this compound and, on the other hand, the modification of this SPCE with metallic gold nanoparticles (AuNPs/SPCE) have led to an increase in the sensitivity of IMP determination. Both sensors have been characterized obtaining good capability of detection (14.1 μM and 0.28 μM for SPCE and AuNPs/SPCE, respectively) and reproducibility (4.75 % and 6.87 % for SPCE and AuNPs/SPCE, respectively) values. The specificity of both sensors towards different compounds has been also analyzed and, the developed electrochemical systems have been successfully applied in the determination of IMP in commercial pharmaceutical preparations. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | spa | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.other | Química analítica | es |
dc.subject.other | Chemistry, Analytic | en |
dc.title | Puesta a punto de un biosensor para la determinación de analitos de interés en el tratamiento de trastornos depresivos: detección electroquímica de imipramina | |
dc.type | info:eu-repo/semantics/bachelorThesis | |
dc.rights.holder | Este documento está sujeto a una licencia de uso Creative Commons, por la cual está permitido hacer copia, distribuir y comunicar públicamente la obra siempre que se cite al autor original y no se haga de él uso comercial ni obra derivada | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
dc.type.hasVersion | info:eu-repo/semantics/acceptedVersion |