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    Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10259/4411

    Título
    Molecular Investigation of Tularemia Outbreaks, Spain, 1997–2008
    Autor
    Ariza Miguel, Jaime
    Johansson, Anders
    Fernández Natal, Isabel
    Martínez Nistal, Carmen
    Orduña, Antonio
    Rodríguez Ferri, F.
    Hernández Pérez, MartaAutoridad UBU Orcid
    Rodríguez Lázaro, DavidAutoridad UBU Orcid
    Publicado en
    Emerging Infectious Diseases. 2014, V. 20, n. 5, p. 754-761
    Editorial
    Centers for Disease Control and Prevention
    Fecha de publicación
    2014-05
    Résumé
    Tularemia outbreaks occurred in northwestern Spain in 1997–1998 and 2007–2008 and affected >1,000 persons. We assessed isolates involved in these outbreaks by using pulsed-field gel electrophoresis with 2 restriction enzymes and multilocus variable number tandem repeat analysis of 16 genomic loci of Francisella tularensis, the cause of this disease. Isolates were divided into 3 pulsotypes by pulsed-field gel electrophoresis and 8 allelic profiles by multilocus variable number tandem repeat analysis. Isolates obtained from the second tularemia outbreak had the same genotypes as isolates obtained from the first outbreak. Both outbreaks were caused by genotypes of genetic subclade B.Br:FTNF002–00, which is widely distributed in countries in central and western Europe. Thus, reemergence of tularemia in Spain was not caused by the reintroduction of exotic strains, but probably by persistence of local reservoirs of infection.
    Materia
    Microbiology
    Microbiología
    URI
    http://hdl.handle.net/10259/4411
    Versión del editor
    https://dx.doi.org/10.3201/eid2005.130654
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    Attribution 4.0 International
    Documento(s) sujeto(s) a una licencia Creative Commons Attribution 4.0 International
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    Ariza-EID_2014.pdf
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