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    Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10259/5518

    Título
    Toxicological evaluation of MnAl based permanent magnets using different in vitro models
    Autor
    Rumbo Lorenzo, CarlosAutoridad UBU Orcid
    Cancho Espina, Cristina
    Popov, Vladimir V.
    Skokov, Konstantin
    Tamayo Ramos, Juan AntonioAutoridad UBU Orcid
    Publicado en
    Chemosphere.2021, V. 263, 128343
    Editorial
    Elsevier
    Fecha de publicación
    2021-01
    ISSN
    0045-6535
    DOI
    10.1016/j.chemosphere.2020.128343
    Résumé
    Due to economic, environmental and geopolitical issues, the development of permanent magnets with a composition free of rare earth elements and with acceptable magnetic properties has been considered a priority by the international community, being MnAl based alloys amongst the most promising candidates. The aim of this work was to evaluate the toxicity of powders of two forms of newly developed MnAl(C) permanent magnets through exposure experiments applying three model organisms, using as a benchmark powders of a commercial rare-earth-containing magnet (Nd2Fe14B). For this purpose, the direct exposure to the different particles suspensions as well as to magnets leachates was evaluated. Both viability and oxidative stress assays were applied in an adenocarcinomic human alveolar basal epithelial cell line (A549) and in the yeast Saccharomyces cerevisiae, together with the bioluminescent inhibition assay in the Gram negative bacterium Vibrio fischeri. The obtained results indicate that MnAl(C) permanent magnets, in general terms, presented similar toxicity than the Nd magnet for the selected biological models under the studied conditions. Overall, the presented data provide, for the first time, an in vitro toxicity analysis of MnAl based magnets.
    Palabras clave
    Magnetic alloys
    Toxicity assays
    Cell lines
    Yeast
    Bacteria
    Materia
    Química orgánica
    Chemistry, Organic
    URI
    http://hdl.handle.net/10259/5518
    Versión del editor
    https://doi.org/10.1016/j.chemosphere.2020.128343
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    Rumbo-chemosphere_2021.pdf
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