| dc.contributor.author | Olmo Alonso, Fabiola | |
| dc.contributor.author | Colina Santamaría, Álvaro | |
| dc.contributor.author | Heras Vidaurre, Aránzazu | |
| dc.date.accessioned | 2025-02-10T09:21:26Z | |
| dc.date.available | 2025-02-10T09:21:26Z | |
| dc.date.issued | 2024-03 | |
| dc.identifier.issn | 0026-265X | |
| dc.identifier.uri | http://hdl.handle.net/10259/10195 | |
| dc.description.abstract | UV–Vis absorption spectroelectrochemistry has been selected as a suitable multiresponse technique to determine
the fluoroquinolone ofloxacin in urine samples without any previous pretreatment. Due to the modification of the
working electrode surface during the oxidation of this antibiotic, the electrode has to be replaced or polished
between measurements. A new spectroelectrochemistry cell has been developed, which allows in an simple way
to perform reproducible experiments with different screen-printed electrodes. The new cell has been used to
perform analysis in a complex matrix such as urine. Due to the trilinear character of the spectroelectrochemical
data, PARAFAC has been used to determine ofloxacin with very good figures of merit, demonstrating the
capability of trilinear methods to avoid the influence of some interfering compounds. | en |
| dc.description.sponsorship | Ministerio de Ciencia e Innovacion ´ and Agencia Estatal de Inves tigacion ´ (Grant numbers: MCIN/AEI/10.13039/501100011033, PID2020-113154RB-C21), Ministerio de Ciencia, Innovacion ´ y Uni versidades (Grant number: RED2022-134120-T), Junta de Castilla y Leon ´ and European Regional Development Fund (Grant number: BU036P23) are gratefully acknowledged for funding this work. | es |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | eng | es |
| dc.publisher | Elsevier | es |
| dc.relation.ispartof | Microchemical Journal. 2024, V. 198, 110186 | es |
| dc.rights | Atribución 4.0 Internacional | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
| dc.subject | Ofloxacin | en |
| dc.subject | Urine | en |
| dc.subject | Spectroelectrochemistry | en |
| dc.subject | Multivariate analysis | en |
| dc.subject.other | Química analítica | es |
| dc.subject.other | Chemistry, Analytic | en |
| dc.subject.other | Electroquímica | es |
| dc.subject.other | Electrochemistry | en |
| dc.title | Determination of ofloxacin in urine using UV/Vis absorption spectroelectrochemistry | en |
| dc.type | info:eu-repo/semantics/article | es |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
| dc.relation.publisherversion | https://doi.org/10.1016/j.microc.2024.110186 | es |
| dc.identifier.doi | 10.1016/j.microc.2024.110186 | |
| dc.journal.title | Microchemical Journal | es |
| dc.volume.number | 198 | es |
| dc.page.initial | 110186 | es |
| dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es |
