ERK dimerization promotes migration and invasion

dc.contributor.author	Fuente Vivas, Dalia de la
dc.contributor.author	Casar, Berta
dc.contributor.author	Crespo, Piero
dc.date.accessioned	2026-10-07T07:56:33Z
dc.date.available	2026-10-07T07:56:33Z
dc.date.issued	2021
dc.identifier.uri	https://hdl.handle.net/10259/12239
dc.description	Póster presentado en: EACR 2021 Virtual Congress, 9-12 June 2021	en
dc.description.abstract	Activation of the Ras-ERK signaling cascade is associated with increased metastasis risk inbreast cancer. In the present study. ERK dimerization plays a crucial role in the migrationand invasion of breast tumor cells. ERK dimers bind to the scaffold protein KSR1 toenhance migration. Blocking ERK dimers formation reduced invasion capacity of MCF-7and MDA-231-MB tumors cells. Thus, targeting ERK dimerization could emerge as a validtherapeutic strategy for the treatment of breast cancer.	en
dc.format.mimetype	application/pdf
dc.language.iso	eng	es
dc.subject.other	Tumores	es
dc.subject.other	Tumors	en
dc.subject.other	Células cancerosas	es
dc.subject.other	Cancer cells	en
dc.title	ERK dimerization promotes migration and invasion	en
dc.type	info:eu-repo/semantics/conferenceObject	es
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es
dc.type.hasVersion	info:eu-repo/semantics/acceptedVersion	es