Development of a methodology to perform toxicokinetics and toxicodynamics studies in biofilms

Abstract

Environmental research has focussed on elucidating and modelling of toxicokinetics and toxicodynamics of different types of nanomaterials in soil and aquatic organisms, and also in biofilms. The first steps towards the developing of a protocol to analyse Multi Component NanoMaterials (MCNMs) and High Aspect Ratio Nanoparticles (HARNs) tokicokinetics and toxicodynamics in biofilms are described here, using P. putida as model organism.