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dc.contributor.authorRubio Presa, Rubén 
dc.contributor.authorPedrosa Sáez, María de los Remedios 
dc.contributor.authorFernández Rodríguez, Manuel A. 
dc.contributor.authorArnáiz García, Francisco Javier 
dc.contributor.authorSanz Díez, Roberto 
dc.date.accessioned2018-09-07T10:20:10Z
dc.date.available2018-10-06T02:45:06Z
dc.date.issued2017-10
dc.identifier.issn1523-7060
dc.identifier.urihttp://hdl.handle.net/10259/4924
dc.description.abstractA novel domino reduction/imine formation/intramolecular cyclization/oxidation for the efficient synthesis of pyrrolo(indolo)[1,2-a]quinoxalines and pyrrolo(indolo)[3,2-c]-quinolines from readily available nitrobenzenes and glycols is reported. The process utilizes the carbonyl byproduct of the initial dioxomolybdenum(VI)-catalyzed reduction of nitroaromatics with glycols as a reagent for the imine generation. This method represents the first sustainable domino reaction for the preparation of biologically relevant heterocycles that internally incorporates the waste formed in the first step to the final product.en
dc.description.sponsorshipJunta de Castilla y León and FEDER (BU076U16) and Ministerio de Economía y Competitividad (MINECO) (CTQ2015-70371-REDT and CTQ2016-75023- C2-1-P)en
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherAmerican Chemical Societyen
dc.relation.ispartofOrganic Letters. 2018, V. 19, n. 19, p. 5470-5473en
dc.subject.otherQuímica orgánicaes
dc.subject.otherChemistry, Organicen
dc.titleMolybdenum-Catalyzed Synthesis of Nitrogenated Polyheterocycles from Nitroarenes and Glycols with Reuse of Waste Reduction By-producten
dc.typeArtículoes
dc.typeinfo:eu-repo/semantics/article
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.relation.publisherversionhttps://doi.org/10.1021/acs.orglett.7b02792
dc.identifier.doi10.1021/acs.orglett.7b02792
dc.relation.projectIDinfo:eu-repo/grantAgreement/JCyL/BU076U16
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/CTQ2015-70371-REDT
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/CTQ2016-75023- C2-1-P
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersionen


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