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dc.contributor.authorSuarez Pantiga, Samuel 
dc.contributor.authorHernández Ruiz, Raquel 
dc.contributor.authorVirumbrales, Cintia 
dc.contributor.authorPedrosa Sáez, María de los Remedios 
dc.contributor.authorSanz Díez, Roberto 
dc.date.accessioned2019-11-13T09:16:22Z
dc.date.available2019-11-13T09:16:22Z
dc.date.issued2019-02
dc.identifier.issn1433-7851
dc.identifier.urihttp://hdl.handle.net/10259/5178
dc.description.abstractThe synthesis of aromatic amines is of utmost importance in a wide range of chemical contexts. We report a direct amination of boronic acids with nitro compounds to yield (hetero)aryl amines. The novel combination of a dioxomolybdenum(VI) catalyst and triphenylphosphine as inexpensive reductant has revealed to be decisive to achieve this new C-N coupling. Our methodology has proven to be scalable, air and moisture tolerant, highly chemoselective and engages both aliphatic and aromatic nitro compounds. More-over, this general and step-economical synthesis of aromatic secondary amines show cases orthogonality to other aromatic secondary amines show cases orthogonality to other aromatic amine syntheses as it tolerates aryl halides and carbonyl compounds.en
dc.description.sponsorshipJunta de Castilla y León (BU022G18),Junta de Castilla y León and FEDER (BU076U16 and BU291P18) and Ministerio de Economía y Competitividad (MINECO) (CTQ2016-75023-C2-1-P)
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.publisherWiley
dc.relation.ispartofAngewandte Chemie International Edition. 2019, V. 58, n. 11, p. 2129-2133
dc.subjectaminationen
dc.subjectboronic acidsen
dc.subjectmolybdenumen
dc.subjectnitro compoundsen
dc.subjectreductionen
dc.subject.otherQuímica orgánicaes
dc.subject.otherChemistry, Organicen
dc.titleReductive molybdenum‐catalyzed direct amination of boronic acids with nitro compoundsen
dc.typeinfo:eu-repo/semantics/article
dc.typeArtículoes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.relation.publisherversionhttps://doi.org/10.1002/anie.201812806
dc.identifier.doi10.1002/anie.201812806
dc.relation.projectIDinfo:eu-repo/grantAgreement/JCyL/U022G18
dc.relation.projectIDinfo:eu-repo/grantAgreement/JCyL/BU076U16
dc.relation.projectIDinfo:eu-repo/grantAgreement/JCyL/BU291P18
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/CTQ2016-75023-C2-1-P
dc.identifier.essn1521-3773
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion


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