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dc.contributor.authorMolinero Abad, Begoña 
dc.contributor.authorPérez Ruiz, Lydia
dc.contributor.authorIzquierdo Bote, Daniel 
dc.contributor.authorEscudero Barbero, Isabel 
dc.contributor.authorArcos Martínez, Julia 
dc.date.accessioned2020-06-17T13:27:02Z
dc.date.available2020-06-17T13:27:02Z
dc.date.issued2019-01
dc.identifier.issn0039-9140
dc.identifier.urihttp://hdl.handle.net/10259/5345
dc.description.abstractThe monitoring of marine dinophysistoxin okadaic acid in seawater can serve as an early alert system for preventing the potential negative effects this toxin can have on the food industry and human health in general. A disposable sensor system for electrochemical detection of this toxin has been developed using screen-printed electrodes. The method described is based on the inhibition of protein phosphatase type 2A by okadaic acid, evaluating the enzyme activity. p-Nitrophenyl phosphate, 4-methylumbelliferyl phosphate and phenyl phosphate have been tested as substrates achieving good limits of detection of 2.7·10–12 M of okadaic acid. The proposed method has been successfully applied to okadaic acid determination in seawater samples. A study of divalent cations present in seawater that can interfere with the measurement has been carried out. The electrode systems were printed on both rigid and textile backing materials to observe the influence of those materials on the final performance of the sensor.es
dc.description.sponsorshipMinisterio de Ciencia e Innovación (MICINN) (TEC2013-405661-P) Ministerio de Economía y Competitividad (MINECO) and European Regional Development Fund (FEDER) (MUSSEL RTC-2015-4077-2).es
dc.format.mimetypeapplication/pdf
dc.language.isoenges
dc.publisherElsevieres
dc.relation.ispartofTalanta. 2019, V. 192, p. 347-352es
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectOkadaic aciden
dc.subjectScreen printed electrodesen
dc.subjectTextile sensorsen
dc.subjectSeawateren
dc.subjectPP2Aen
dc.subject.otherQuímica analíticaes
dc.subject.otherChemistry, Analyticen
dc.titleSensor system based on flexible screen-printed electrodes for electrochemical detection of okadaic acid in seawateren
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://doi.org/10.1016/j.talanta.2018.09.072es
dc.identifier.doi10.1016/j.talanta.2018.09.072
dc.relation.projectIDinfo:eu-repo/grantAgreement/MICINN/TEC2013-405661-P
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/MUSSEL RTC-2015-4077-2)
dc.journal.titleTalantaes
dc.volume.number192es
dc.page.initial347es
dc.page.final352es
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersiones


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