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dc.contributor.authorOlmo Alonso, Fabiola
dc.contributor.authorGaroz Ruiz, Jesús 
dc.contributor.authorCarazo, Julia
dc.contributor.authorColina Santamaría, Álvaro 
dc.contributor.authorHeras Vidaurre, Aránzazu 
dc.date.accessioned2021-11-08T12:21:53Z
dc.date.available2021-11-08T12:21:53Z
dc.date.issued2020-09
dc.identifier.issn1424-8220
dc.identifier.urihttp://hdl.handle.net/10259/6121
dc.description.abstractUV/Vis absorption spectroelectrochemistry (SEC) is a multi-response technique that has been commonly used for the characterization of materials and the study of reaction mechanisms. However, it has been scarcely used for quantitative purposes. SEC allows us to obtain two analytical signals simultaneously, yielding a dual sensor in just one experiment. In the last years, our group has developed new devices useful for analysis. In this work, a SEC device in parallel configuration, based on optical fibers fixed on screen-printed electrodes, was used to determine isoprenaline in a commercial drug, using both, the electrochemical and the spectroscopic signals. In this commercial drug, isoprenaline is accompanied in solution by other compounds. Among them is sodium metabisulfite, an antioxidant that strongly interferes in the isoprenaline determination. A simple pretreatment of the drug sample by bubbling wet-air allows us to avoid the interference of metabisulfite. Here, we demonstrate again the capabilities of UV/Vis absorption SEC as double sensor for analysis and we propose a simple pretreatment to remove interfering compounds.en
dc.description.sponsorshipMinisterio de Economía y Competitividad (Grant CTQ2017-83935-R-AEI/FEDERUE), Junta de Castilla y León (Grant BU297P18), and Ministerio de Ciencia, Innovación y Universidades (Grant RED2018-102412-T). F.O. is grateful for the contract funded by Junta de Castilla y León, the European Social Fund and the Youth Employment Initiative. J.G.R. thanks Ministerio de Economía y Competitividad for his postdoctoral contract (Grant CTQ2017-83935-R AEI/FEDER, UE).en
dc.format.mimetypeapplication/pdf
dc.language.isoengen
dc.publisherMDPIes
dc.relation.ispartofSensors. 2020, V. 20, n. 18, 5179es
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectSpectroelectrochemistryen
dc.subjectElectrochemistryen
dc.subjectUV/Vis absorptionen
dc.subjectDrug analysisen
dc.subjectIsoproterenolen
dc.subjectMetabisulfiteen
dc.subject.otherQuímica analíticaes
dc.subject.otherChemistry, Analyticen
dc.titleSpectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sampleen
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://doi.org/10.3390/s20185179es
dc.identifier.doi10.3390/s20185179
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones


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