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dc.contributor.author | Fernández-Lázaro, Diego | |
dc.contributor.author | Seco-Calvo, Jesús | |
dc.contributor.author | Pascual-Fernández, Jorge | |
dc.contributor.author | Domínguez-Ortega, Carlos | |
dc.contributor.author | Valle Soto, Miguel del | |
dc.contributor.author | Mielgo Ayuso, Juan | |
dc.date.accessioned | 2023-03-22T07:43:23Z | |
dc.date.available | 2023-03-22T07:43:23Z | |
dc.date.issued | 2022-12 | |
dc.identifier.uri | http://hdl.handle.net/10259/7578 | |
dc.description.abstract | Tribulus terrestris L. (TT) ingredients have anti-inflammatory and antioxidant activities, but their effects on exercise-induced muscle damage (EIMD) in trained athletes are uncertain. The purpose of this single-blind placebo-controlled trial, in accordance with CONSORT guidelines, was to examine the effect of 6 weeks of TT supplementation on muscle metabolism, inflammation biomarkers, and oxidant status. Thirty trained male CrossFit® athletes were randomly assigned to be supplemented with 770 mg/day of TT (intervention group (IG)) or receive a placebo daily (control group (CG)) for 6 weeks. Muscle damage enzymes, inflammation biomarkers, and Total Antioxidant Status (TAS) were assessed at baseline (T1), 21 days after baseline (T2), and after 42 days (T3). Grace, a Workout of the Day, was measured in T1 and T3. Statistical significance (p < 0.05) was found between IG and CG in Lactate Dehydrogenase (LDH), C-reactive protein (CRP), and TAS levels at the end of the follow-up. Furthermore, TAS levels were significantly (p < 0.05) lower at T2 and T3 relative to baseline in the IG, also LDH and CRP increased significantly (p < 0.05) at T2 and T3 relative to baseline in the CG. No significant (p > 0.05) decreases in muscle damage or inflammation biomarkers were observed, although a slight downward trend was observed after 6 weeks for supplemented athletes. TT supplementation could attenuate the CrossFit® training program-induced oxidative stress, muscle damage, and inflammation which could be due to the natural antioxidant and anti-inflammatory properties of TT. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | es |
dc.publisher | MDPI | en |
dc.relation.ispartof | International Journal of Environmental Research and Public Health. 2022, V. 19, n. 23, 16158 | en |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Tribulus terrestris L. | en |
dc.subject | Herbal supplementation | en |
dc.subject | Crossfit | en |
dc.subject | Muscle damage | en |
dc.subject | Inflammation response | en |
dc.subject | Exercise-induced oxidative stress | en |
dc.subject.other | Fisiología | es |
dc.subject.other | Physiology | en |
dc.title | 6-Week Supplementation with Tribulus terrestris L. to Trained Male CrossFit® Athletes on Muscle, Inflammation, and Antioxidant Biomarkers: A Randomized, Single-Blind, Placebo-Controlled Trial | en |
dc.type | info:eu-repo/semantics/article | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.relation.publisherversion | https://doi.org/10.3390/ijerph192316158 | es |
dc.identifier.doi | 10.3390/ijerph192316158 | |
dc.identifier.essn | 1660-4601 | |
dc.journal.title | International Journal of Environmental Research and Public Health | en |
dc.volume.number | 19 | es |
dc.issue.number | 23 | es |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es |