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dc.contributor.authorVirumbrales, Cintia 
dc.contributor.authorSolas Luera, Marta 
dc.contributor.authorSuarez Pantiga, Samuel 
dc.contributor.authorFernández Rodríguez, Manuel A. 
dc.contributor.authorMarín Luna, Marta
dc.contributor.authorSilva López, Carlos
dc.contributor.authorSanz Díez, Roberto 
dc.date.accessioned2020-01-23T12:46:56Z
dc.date.available2020-01-23T12:46:56Z
dc.date.issued2019-12
dc.identifier.issn1477-0520
dc.identifier.urihttp://hdl.handle.net/10259/5213
dc.description.abstractThe stereospecific gold(I)-catalyzed nucleophilic cyclization of β-monosubstituted o-(alkynyl)styrenes to produce C-1 functionalized 1H-indenes including challenging substrates and nucleophiles, such as β-(cyclo)alkyl-substituted o-(alkynyl)styrenes and a variety of alcohols as well as selected electron-rich aromatics, is reported. DFT calculations support the stereochemical outcome of the process that involves the formation of a key cyclopropyl gold carbene intermediate through a regiospecific 5-endo cyclization.en
dc.description.sponsorshipMinisterio de Economía y Competitividad (MINECO) and FEDER (CTQ2016-75023-C2-1-P and 2-P), and Junta de Castilla y León and FEDER (BU291P18) and Xunta de Galicia (ED431C 2017/70 and ED431E 2018/07)es
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherRoyal Society of Chemistry
dc.relation.ispartofOrganic & Biomolecular Chemistry. 2019, V. 17, n. 46, p. 9924-9932
dc.subject.otherQuímica orgánicaes
dc.subject.otherChemistry, Organicen
dc.titleGold(i)-catalyzed nucleophilic cyclization of β-monosubstituted o-(alkynyl)styrenes: a combined experimental and computational studyen
dc.typeinfo:eu-repo/semantics/article
dc.rights.accessRightsinfo:eu-repo/semantics/embargoedAccess
dc.relation.publisherversionhttps://doi.org/10.1039/C9OB02126D
dc.identifier.doi10.1039/C9OB02126D
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/CTQ2016-75023-C2-1-P
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/CTQ2016-75023-C2-2-P
dc.relation.projectIDinfo:eu-repo/grantAgreement/JCyL/BU291P18
dc.relation.projectIDinfo:eu-repo/grantAgreement/XG/ED431C 2017/70
dc.relation.projectIDinfo:eu-repo/grantAgreement/XG/ED431E 2018/07)
dc.identifier.essn1477-0539
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion


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