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    Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10259/5242

    Título
    Intestinal fructose and glucose metabolism in health and disease
    Autor
    Perdomo Hernández, Germán M.UBU authority Orcid
    Merino, Beatriz
    Fernández Díaz, Cristina M. .
    Cózar Castellano, Irene
    Publicado en
    Nutrients. 2020, V. 12, n. 1, 94
    Editorial
    MDPI
    Fecha de publicación
    2020-01
    DOI
    10.3390/nu12010094
    Abstract
    The worldwide epidemics of obesity and diabetes have been linked to increased sugar consumption in humans. Here, we review fructose and glucose metabolism, as well as potential molecular mechanisms by which excessive sugar consumption is associated to metabolic diseases and insulin resistance in humans. To this end, we focus on understanding molecular and cellular mechanisms of fructose and glucose transport and sensing in the intestine, the intracellular signaling effects of dietary sugar metabolism, and its impact on glucose homeostasis in health and disease. Finally, the peripheral and central effects of dietary sugars on the gut–brain axis will be reviewed.
    Palabras clave
    fructose
    glucose
    small intestine
    liver
    brain
    gut-brain axis
    non-alcoholic fatty liver
    insulin resistance
    metabolic syndrome
    type 2 diabetes mellitus
    Materia
    Endocrinología
    Endocrinology
    URI
    http://hdl.handle.net/10259/5242
    Versión del editor
    https://doi.org/10.3390/nu12010094
    Collections
    • Artículos DIABO-TER
    Atribución 4.0 Internacional
    Documento(s) sujeto(s) a una licencia Creative Commons Atribución 4.0 Internacional
    Files in this item
    Nombre:
    Merino-nutrients_2020.pdf
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    21.67Mb
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